On August 26, 1936 ground was broken for a new Coast Guard Station on the Manasquan Inlet in Point Pleasant Beach. The recently completed Manasquan Inlet project had made relocation to Point Pleasant Beach desirable by the Coast Guard for construction of the new modern station and accompanying boat house.

The $42,000 project was completed in December 1937 and the official opening of new Station #105 took place on January 30, 1938 with much fanfare. Later in 1938 work started on the Boathouse, which included a launch ramp, workshop and garage. The Boathouse opened in 1939.

In 1976, an enlisted quarters was built next to the station. Then, in 2017, Coast Guard Manasquan Inlet began construction of a new station nearby. The old station was decommissioned in 2018 and was sold to the borough of Point Pleasant Beach in August 2023. It is listed on both the State and National Historic Registers.

The old Manasquan Inlet Lifeboat Station 105 is historically significant in that it is one of five identical or nearly indentical stations of the Roosevelt-type construction built in New Jersey during the Depression years of the 1930s. This type station was also constructed at this time along both coasts of the United States.

Manasquan Inlet Lifeboat Station 105 stands as a landmark at the northern terminus of the Intra-Coastal Waterway. Its attractive, distinct architecture makes this building an extremely valuable part of Point Pleasant Beach, as well as and the rich maritime history of this part of the Borough.